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It is typically characterized by congenital microcephaly, intractable seizures of infantile onset, and severe psychomotorretardation.
2
The poor test performance was mainly associated with psychomotorretardation and decreased concentration in depressed individuals.
3
The psychomotorretardation is thought to be caused by impaired neuronal T3 uptake during brain development.
4
In addition, data have indicated significantly improved psychomotorretardation in patients with depression after 3 months of treatment.
5
Clinically, half of the patients presented with severe AIDS dementia complex including advanced psychomotorretardation and behavioural dysfunction.
1
Compared with placebo, maprotiline induced psychomotorimpairment on both objective and subjective assessment in a dose related manner.
1
Results were not moderated by sociodemographic background variables, psychomotorslowing and psychopathological symptoms other than thought disorder.
2
Psychomotorslowing test findings were independent from peripheral nervous system damage indicating uncorrelated disturbances of CNS and PNS function in HIV-1 infection.